First, they’re living in very different conditions. One theory is that children in first world countries may not have had their immune systems properly “primed” by exposure to allergens at a young age. They grow up in environments that are too sterile.

And second, I’m quite sure that allergies in the third world are vastly under-reported. Who cares if you get a runny nose every spring, when you’re worried about getting enough food on your plate? In first world countries we have the luxury of saying, “Gee, little Jimmy seems a tad hyperactive, maybe I should get him tested for allergies.”

It’s apples and oranges.

As for the original question, I think it comes down to a matter of individual conscience. But I must say I find the harlequin condition to be quite horrifying, and I personally would get prenatal screening before having a second child. A 25 percent chance would be too high for me.

While looking at this subject let me introduce the infection of Cholera and how cystic fibrosis seemed to have been the genetic answer for this disease even though, today we see this adaptive evolutionary maneuver as a disease as well. Our bodies adapt even in the most unusual ways to uncertain changes?

Answer me this… Why do people in Developed Countries have allergies while those who live in undeveloped countries do not have allergies? I help you understand. Our production of IgE from our mast cell help us to fight what… pollen? Cause us horrible anaphylactic shock? Maybe but in countries that are undeveloped have, “Bugs” trypanosomes, amoebas, bot flies etc, is actually what our IgE is supposed to attack…These Parasites and bugs are what our mast cells search and destroy. Imagine if scientists find a way to breed out or destroy a designer babies Ige and Mast Cells so they don’t have to worry about a stuffy nose? Great, Huh? Are you sure? Think down the road maybe 20-30 years after IgE and our mast cells have been almost completely obliterated from the gene pool as our designer children are walking around.

Susie, a child with no IgE, Starts to get sick after playing in the mud making mud pies. They aren’t sure why she is sick so they take her to the doctor. She is now going into shock and they discover she isn’t alone. In her brain and her body they find Balamuthia mandrillaris and many round worms. Her IgE isn’t there so she has no way to fight against these little hijackers. She gets many rounds of antibiotics and many months later she is starting to recover after the attack of the brain eating amoeba and the round worms.

Jimmy is being checked in the doctor after feeling sick to his stomach and his massive weight loss is traumatic he too has no IgE and unfortunately dies from a tape worm. Think about this if we have no IgE or anyway to fight parasitic invaders in the future what kind of worm is waiting for the right moment to invade our bodies and wipes out most of our population similar to the black plague so long ago…

Be ready things are changing even if we think it is good to get rid of allergies by getting rid of our IgE and our Mast Cells a worm may be ready to cause another pandemic killing Billions!

Designer babies aren’t the answer and this is only a scratch to the surface on genetic recombination so parents can pick and chose what they want their child to have. Some choices that can be made now can be the end much later on. To be honest I’m thankful I have a stuffy nose I know that I still have histamines that are ready to kill a mini-invader? I still am learning about what happens when people can pick and chose what genes they want their babies to have and so far it seems scary. I hope people really start noticing that picking your babies hair colour may also be picking a fatal recombination of their genes… I could go on forever with this though.